Stereotactic Body Radiotherapy (Sbrt) as a New Standard of Care for Spinal Metastases

Grant number: 1141566 | Funding period: 2018 - 2020

Completed

Abstract

Secondary spread of cancer to the spine affects about 40% of all cancer patients. The current standard of care, radiotherapy, does not provide durable control of cancer pain. Breakthrough technology in stereotactic body radiotherapy (SBRT) is showing considerable promise for improved patient outcomes. This study is a multi-national collaboration between Australia and Canada directly comparing conventional radiotherapy to spinal SBRT in order to establish spinal SBRT as the new standard of care.

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Vertebral Stereotactic ablative body radiotherapy (SABR) involves substantial tumour density heterogeneities. We evaluated the imp..

Stereotactic body radiotherapy versus conventional external beam radiotherapy in patients with painful spinal metastases: an open-label, multicentre, randomised, controlled, phase 2/3 trial

A Sahgal, SD Myrehaug, S Siva, GL Masucci, PJ Maralani, M Brundage, J Butler, E Chow, MG Fehlings, M Foote, Z Gabos, J Greenspoon, M Kerba, Y Lee, M Liu, SK Liu, I Thibault, RK Wong, M Hum, K Ding

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Background: Conventional external beam radiotherapy is the standard palliative treatment for spinal metastases; however, complete ..

University of Melbourne Researchers

Shankar Siva

Tomas Kron

David Ball